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T he topic has become the mainstay of dystopian science fiction. Our world is afflicted by widespread infertility and childless civilisations are left hovering on the brink of collapse. Yet the scenarios outlined in these books and dramatisations may be less fanciful than is first supposed. Indeed, reaction to a study of male infertility, published last week, suggests we may already be hurtling towards such a fate. According to scientists at the Hebrew University of Jerusalem, sperm counts among men in the west have more than halved in the past 40 years and are currently falling by an average of 1. Humanity could soon become extinct, it was claimed by some commentators.
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Hopes for a male contraceptive pill have increased after a trial showed a once-daily capsule appeared to work with no significant side-effects. The drug aims to suppress levels of hormones that drive the production of sperm and testosterone in the testes. In the month-long study, doctors found that levels of the hormones required for sperm production fell in men who took the daily capsule, suggesting their sperm counts had been markedly reduced. The next step will be to confirm the fall and determine if it is sufficient. Scientists have been searching for a male contraceptive pill for years, testing numerous pills , injections and gels to find an alternative to condoms and vasectomies. We are neglecting a major potential user population with the limited options currently available to men. Ten volunteers received a placebo capsule; the rest were assigned a mg or mg dose of the drug, beta-MNTDC.
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